What to know if you test positive for COVID-19
Antiviral medicines such as Paxlovid (nirmatrelvir plus ritonavir) and remdesivir can lower the risk of severe COVID-19 in eligible people. These treatments are most effective when started early in the course of illness. If you test positive and have risk factors for severe disease, contact a healthcare professional right away to discuss whether treatment is appropriate. Acting quickly matters, because prescriptions for COVID-19 medicines must be issued promptly to be most beneficial.
When antiviral treatment is recommended
COVID-19 antiviral treatment is generally recommended for people at higher risk of progressing to severe disease. Eligibility depends on age, underlying conditions, vaccination status, and time since symptom onset. Even if you are up to date with vaccinations, treatment may be considered based on clinical evaluation. A healthcare professional will weigh benefits and potential drug interactions before prescribing.
Common eligibility considerations
- Age 65 or older
- Chronic lung or heart disease, diabetes, or weakened immune system
- Higher body weight or pregnancy
- Not completed or not up to date with COVID-19 vaccinations
Available COVID-19 treatment options
Several antiviral and monoclonal antibody options have been authorized in various regions. Availability and recommended use vary by country and local guidelines. Treatment choice depends on kidney or liver function, other medications you take, and whether you can start therapy soon after symptoms begin.
| Medicine | Type | Typical Treatment Duration | Setting |
|---|---|---|---|
| Paxlovid (nirmatrelvir/ritonavir) | Oral antiviral | 5 days | Home or clinic |
| Remdesivir | Intravenous antiviral | 3 days | Clinic or hospital |
| Molnupiravir | Oral antiviral | 5 days | Home |
How a prescription for COVID-19 medicine works
In most cases, a clinician evaluates symptoms, confirms a positive test, and reviews medical history before prescribing. Telehealth visits can be appropriate for assessment and prescription when in-person care is not practical. After prescribing, pharmacy processing and prior authorization (if required) may affect how quickly you receive the medicine.
Steps to get a prescription
- Get tested and confirm a positive result
- Contact a healthcare provider or telehealth service
- Discuss risk factors, symptoms, and current medications
- Follow instructions for pick-up or home delivery
Potential benefits and side effects
Antiviral treatments reduce the likelihood of hospitalization and death when used in eligible people. Common side effects are usually mild and vary by drug. For example, Paxlovid can interact with many medications, making a review of current prescriptions important. Remdesivir may cause infusion-related reactions. Molnupiravir is typically reserved for when other options are not suitable.
Where to get COVID-19 prescriptions filled
You can fill COVID-19 prescriptions at most retail pharmacies or through mail-order services. In some regions, community testing and treatment sites provide free medicine. If you need support with cost, patient assistance programs offered by manufacturers or local health departments may help. Check with your insurer about coverage and any prior authorization requirements.
Prevention and follow-up care
Vaccination and staying up to date with boosters lower the risk of severe outcomes. If you are prescribed an antiviral, complete the full course and monitor for worsening symptoms. Seek emergency care immediately for difficulty breathing, persistent chest pain, or confusion. Follow up with your clinician if symptoms do not improve or new concerns arise.