Overview and purpose of the NASA bed rest studies
The NASA bed rest studies simulate microgravity effects on the human body by requiring participants to remain in bed with their heads tilted downward. Conducted at the University of Texas Medical Branch (UTMB) for NASA, these research campaigns aim to understand physiological changes during spaceflight and to test countermeasures. The 2019 campaigns were part of ongoing research to improve astronaut health and inform future long-duration missions. Below is a detailed, evergreen guide to applying and participating.
2019 study campaigns and study phases
In 2019, NASA supported a pair of bed rest campaigns at UTMB, each involving different intervention focuses. Studies were structured in sequential phases that increased in constraint to simulate long-duration spaceflight conditions.
Baseline and pre-bed period
Before bed rest begins, participants complete baseline testing that includes bloodwork, imaging, strength assessments, balance, and cognitive tests. During the pre-bed period, subjects may follow prescribed exercise and diet regimens to establish a consistent starting state.
60-day and 88-day bed rest blocks
The core of each campaign is a prolonged bed rest period at a six-degree head-down tilt. Participants must keep at least one shoulder in contact with the mattress at all times and perform daily activities such as eating, reading, and hygiene while horizontal. Researchers collect physiological data continuously and periodically test countermeasures like resistive exercise and vibration therapy.
Rehab and follow-up
After bed rest, participants undergo a structured rehabilitation phase to regain mobility and strength. Follow-up testing over weeks or months assesses the persistence of effects and the success of countermeasures.
Eligibility criteria for 2019 campaigns
NASA and UTMB applied consistent, science-based criteria to ensure the sample reflected the populations relevant to spaceflight research. These standards were enforced across 2019 study cycles.
| Attribute | Verified Detail (typical for 2019 campaigns) | Source Type |
|---|---|---|
| Age range | 24–55 years old at study start | UTMB/NASA study notices |
| Sex | Both males and females; campaigns sometimes separated by sex | UTMB recruitment materials |
| Height | At least 5 feet (152.4 cm) and no more than 6 feet 2 inches (188 cm) | UTMB screening documents |
| Health | Non-smoking, normal BMI (typically 19–30), no orthostatic intolerance | Medical screening guidelines |
| Drugs/medications | No restricted medications; prescription use reviewed case-by-case | UTMB screening checklist |
Study locations and facilities
The 2019 NASA bed rest studies were conducted primarily at the UTMB Institute for Translational Sciences in Galveston, Texas. The facility includes a dedicated bed rest wing with controlled lighting, individualized patient rooms, and on-site research and medical staff. Volunteers live in the unit for the duration of the bed rest period, which can span multiple months, depending on the campaign.
Study phases and timelines (illustrative example)
Below is a generalized sequence that reflects typical 2019 campaign structures. Exact dates vary by campaign; refer to official notices for precise scheduling.
| Date or Period | Event | Why it matters |
|---|---|---|
| Screening (1–2 weeks) | Medical, psychological, and fitness assessments | Ensures participant safety and data validity |
| Baseline (1–2 weeks) | Inpatient testing before bed rest begins | Establishes pre-intervention reference measurements |
| Bed rest (60 or 88 days) | Head-down tilt with daily activities conducted in bed | Simulates microgravity physiological effects |
| Rehab (1–2 weeks) | Progressive mobilization and physical therapy | Supports safe return to normal mobility |
| Follow-up (weeks to months) | Remote and in-person assessments after discharge | Measures long-term recovery and intervention effects |
Compensation and costs
Participants receive a structured compensation schedule tied to study milestones. Travel to and lodging at the UTMB facility is typically covered, and a defined per-diem is provided during the inpatient stay. Exact amounts vary by campaign and by time spent in each phase; official recruitment notices list the current compensation tiers. Note that bed rest is an inpatient commitment that requires a substantial time investment and significant adjustment to daily routines.
What to expect during a typical day
While in strict bed rest, participants perform all essential activities in a lying-down position. Meals are delivered to the bedside, hygiene routines are adapted to limited mobility, and researchers schedule regular tests and exercises. Participants may use laptops, read, watch media, and engage in structured cognitive tasks. Adherence to the head-down tilt and activity restrictions is critical for data quality.
Risks and considerations
Prolonged bed rest and head-down tilt can cause musculoskeletal deconditioning, fluid shifts, orthostatic challenges upon re-ambulation, and temporary back discomfort. UTMB provides supervised rehabilitation and medical monitoring to mitigate these effects. Individuals with a history of orthostatic intolerance, certain cardiovascular conditions, or unstable mental health may not be eligible. Full disclosure during screening helps ensure safety.
How to find official application details
NASA periodically posts recruitment notices for bed rest studies on agency career and research partner sites. The official UTMB research website and NASA human research program pages are the most reliable sources for upcoming study windows, exact application deadlines, and document checklists. Aspiring participants should prepare to provide medical records, identification, and details about current medications during the application process.